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The brain and neuroscience
The brain and neuroscience: memory, consciousness and behaviour, brain disease and neural interfaces.
- Intensified breathing exercises cause emotional release
An experiment demonstrated that high ventilation breathwork can trigger psychedelic-like experiences, including ego dissolution and perceptual alterations.
- 301.4 million people globally live with anxiety disorders
Stress degrades perineuronal nets in the bed nucleus of stria terminalis, which exacerbates anxiety behavior in adult male mice. Restoring these structures helps normalize stress responses.
- Knockout of TMEM63B reduces heat sensitivity
Removing the TMEM63B channel from dorsal root ganglion neurons significantly reduced heat sensitivity and raised the temperature required to trigger action potentials.
- New method reveals how brain states evolve over time
The new method combines spatial ICA with dynamic analysis to reveal evolving connectivity patterns invisible to discrete-state models. Validation on the FBIRN dataset (151 subjects) confirmed recovery of continuous overlaps and higher-order coupling structures.
- Ovarian structure changes up to age 75
A study of 28 women aged 50 to 75 revealed that ovaries continue structural remodeling, metabolism, and immune activity decades after reproduction ends. This contradicts the long-held belief that the organ becomes an inert remnant following reproductive cessation.
- MRI captures directional fluid movement
Researchers found that spontaneous infraslow hemodynamic oscillations during sleep coordinate spatially structured, directional CSF flow in both ventricular and subarachnoid compartments.
- Study reveals how brain cells encode word meaning
A study found that neural activity patterns matching large language models like ChatGPT and Gemini reflect how the brain encodes word meaning.
- Project uses magnetic carrier for autonomous robotic implantation of electronics
The MINIGRAPH consortium created graphene electrodes and a magnetic robotic implantation system, passing accelerated stability tests projecting over 10 years of operation.
- Functional connectivity reveals differences in Alzheimer's patients
Researchers found distinct patterns in functional connectivity changes between healthy elderly individuals and Alzheimer's disease patients. Until effective treatments for neurodegenerative conditions become available, these differences remain a subject of scientific debate regarding dysfunction versus compensation.
- Linear model underperforms at cross-area inpainting
Researchers introduced a linear variant of the NeuroPaint autoencoder to align neural dynamics across different recording sessions. While the model achieved strong predictive performance on recorded areas, it was less accurate than nonlinear models at inpainting activity in unrecorded regions.
- Study of 12.4 million immune cells reveals determinants of immune aging
A study of 2,600 individuals found that the ratio of GZMK+ to GZMB+ T cells predicts health outcomes. Genetic and environmental factors drive differences in immune aging between people of the same age.
- SpikeSSL fixes spike inference errors
Researchers developed the universal SpikeSSL framework, which uses bidirectional state-space layers to improve spike inference accuracy across diverse calcium indicators.
- Cala kIQ Plus System available nationwide with prescription
The FDA-cleared Cala kIQ Plus device offers three stimulation waveform modes, resulting in tremor reduction for 76–89% of participants in a recent study.
- 2026 Nobel Prize: Discoveries of light-gated ion channels and optogenetics
Karl Deisseroth, Peter Hegemann, and Georg Nagel received the prize for discovering light-gated ion channels and optogenetics, enabling millisecond-scale neuronal control.
