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Psilocybin forms stable dendritic spines within 24 hours

Research found psilocybin triggers rapid growth of dendritic spines within 24 hours, transforming them from fragile to stable structures. The structural neuroplasticity mechanism operates independently of hallucinogenic effects.

Field
the brain and neuroscience
What they did
Researchers from the University of California, Santa Cruz, demonstrated that psilocybin rapidly accelerates the maturation of dendritic spines in living brains, transforming them from unstable to stable structures within 24 hours.
Why it matters
This finding helps explain how neural connections are restored in depressed brains and those affected by chronic stress, while operating independently of the substance's hallucinogenic properties.
#psilocybin#dendritic spines#neuroplasticity#depression#synaptic maturation

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