RealFeedApp TrUDI generates 250 times more detected fluorescence photons
Researchers at Rockefeller University developed the TrUDI system, increasing detected fluorescence photons by 250 times compared to previous approaches. This enabled single-cell-resolution recording of neuronal population activity at approximately 2 mm depth in living mice without surgically removing the overlying cortex.
- Field
- the brain and neuroscience
- What they did
- Researchers at Rockefeller University developed the TrUDI method, which allows recording neuronal activity in the deep brain of living mice at a depth of approximately 2 mm without surgically removing the cortex.
- Why it matters
- This enables single-cell-resolution recordings, which were previously impossible due to light scattering in deep brain layers.
#three-photon microscopy#trudi#neuronal activity#deep brain imaging#rockefeller university
