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Researchers restored more than two hours of sleep in mice

Researchers from the University of Kentucky found that overactive immune cells in the brain cause sleep disruption in Alzheimer's disease. Removing these cells in mice with Alzheimer's-like brain changes restored more than two hours of daily sleep without clearing amyloid plaques.

Field
the brain and neuroscience
What they did
Researchers discovered that in mice with Alzheimer's-like brain changes, immune cells in the brain become overactive. By temporarily removing these cells, more than two hours of sleep per day were restored in the mice without removing the amyloid plaques.
Why it matters
This discovery may help explain why Alzheimer's disease disrupts sleep and suggest a promising new target for treatment, as the problem appears to be reversible.
#alzheimer's#sleep#immune cells#amyloid plaques#university of kentucky

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