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New drug failed to reduce heart attack deaths

The ZEUS study found that ziltivekimab reduced interleukin-6 levels without decreasing heart attacks, strokes, or deaths. Novo Nordisk halted two additional trials, yet cardiologists plan to pursue anti-inflammatories for cardiovascular and metabolic disease.

Field
drugs and trials
What they did
Researchers demonstrated that an experimental drug reduced inflammation markers but failed to prevent heart attacks, strokes, or death in patients with severe illness.
Why it matters
This is important for cardiologists because the results help explain why some drugs lower inflammation markers without providing clinical benefit in real patients.
#inflammation#cardiovascular disease#ziltivekimab#zeus#interleukin-6#clinical trial

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