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Drugs and trials
Drugs and clinical trials: new medicines, trial results and regulator decisions.
- Eurofins developed over 100 ADCs for clinical trials
ADC development remains complex and empirical, requiring linker chemistry, DAR, and stability optimization. Eurofins Discovery offers specialized linker synthesis for clinical trials.
- TNV313 Phase 1 study doses first subject
Tenvie Therapeutics initiated Phase 1 first-in-human trials for TNV313, a small molecule NLRP3 inhibitor designed to cross the blood-brain barrier. The company plans to publish preliminary safety and pharmacokinetic data in the first half of 2027.
- FDA warned against using sexual enhancement product Rhino 7S Type F3 7000
The FDA warned consumers about products containing undeclared ingredients, including sildenafil (Viagra's active ingredient) and acetaminophen (Tylenol).
- Study evaluates safety and dosing of siRNA molecule
Researchers are testing a small interfering RNA molecule designed to reduce prion protein production. This marks the first human trial for this treatment.
