RealFeedApp Cone OS material is removed in small successive particles
Live imaging in zebrafish revealed that cone outer segments release successive particles that are rapidly internalized by the RPE for degradation.
- Field
- the brain and neuroscience
- What they did
- Researchers showed for the first time in a living animal that cone photoreceptor segments are removed not as a whole, but as a series of small particles that are quickly absorbed by pigment epithelial cells.
- Why it matters
- This knowledge helps understand vision aging mechanisms, as disruption of this process leads to waste accumulation and vision loss.
#photoreceptor#retinal pigment epithelium#zebrafish#cone outer segment#live imaging
