RealFeedApp Mutated tau proteins aggregate into fibrils faster
Researchers from the University of North Carolina and the University of California found that water in brain cells promotes tau protein misfolding into fibrils that kill neurons.
- Field
- the brain and neuroscience
- What they did
- Researchers discovered that specific areas on tau proteins repel water, and when that water evaporates, the proteins clump together into rigid threads that kill brain cells.
- Why it matters
- This explains the mechanism of how the tau protein spreads through the brain in Alzheimer's disease, which was previously a mystery.
#tau protein#amyloid-beta#alzheimer's#misfolding#water#fibrils
