RealFeedApp Split-1POK records cellular activity onto a protein tape
Researchers introduced split-1POK, a split protein that reconstitutes into a growing protein tape in live cells, enabling scalable recording of calcium dynamics and molecular interactions under standard light microscopy.
- Field
- genetics and genomes
- What they did
- Scientists created a new protein fragment called split-1POK, which reassembles into a single structure when its two parts interact, recording cellular activity onto a protein tape.
- Why it matters
- This enables simultaneous tracking of calcium ion dynamics and transient molecular interactions in live cells using standard light microscopy.
#synthetic biology#calcium dynamics#protein tape#single cell recording
