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New DCIS map shows surrounding cells and structures

Researchers at MD Anderson constructed a detailed map of the tumor microenvironment to explain why some ductal carcinoma in situ lesions progress to invasive disease while others do not. The study highlights specific cellular structures that influence the biological pathway toward invasion.

Field
cancer research
What they did
Researchers created a detailed map of the tumor microenvironment surrounding preinvasive breast cancer (DCIS) by analyzing tissue samples from healthy women, DCIS patients, and those with invasive cancer.
Why it matters
This map may help explain why some lesions progress to invasive cancer while others do not, and inform strategies to improve patient risk prediction.
#breast cancer#ductal carcinoma in situ#tumor microenvironment#md anderson#risk prediction

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