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Glymphatic drainage declines with age

Decline in cerebrospinal fluid drainage through the glymphatic system correlates with aging and negatively impacts patients with Alzheimer's disease.

Field
the brain and neuroscience
What they did
Researchers confirmed that cerebrospinal fluid flows through the brain and is drained out of it, especially during sleep, and that this process is responsible for removing metabolic waste, including protein aggregates linked to Alzheimer's disease.
Why it matters
The decline in this drainage efficiency with age and in neurodegenerative conditions makes it an important factor in brain aging, which opens new avenues for developing treatment methods.
#glymphatic system#alzheimer's disease#cerebrospinal fluid#aging#amyloid-beta

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