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Mitofusin activators extend life in nematode worms

Research shows MTR4 reduces vascular cellular senescence in mammals, while mitofusin activators extend lifespan in nematodes.

Field
ageing and longevity
What they did
Researchers found that mitofusin activators extend the lifespan of nematode worms, while MTR4 inhibitors reduce vascular cellular senescence in mammals.
Why it matters
These findings could help develop methods to combat age-related diseases by controlling aging mechanisms through mitochondrial and cellular senescence intervention.
#senescence#mitofusin#mammals#nematodes#longevity

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