RealFeedApp Nuclear DNA structure alters gene expression with age
Inhibiting the H3K9me3 epigenetic modification reduced neuronal damage and amyloid accumulation in mouse models. The intervention improved cognitive function and reduced pathological markers associated with the disease.
- Field
- the brain and neuroscience
- What they did
- Researchers found that inhibiting the epigenetic modification H3K9me3 reduces pathological changes in mouse models of Alzheimer's disease.
- Why it matters
- This could help understand brain aging mechanisms and identify new targets for treating neurodegenerative diseases.
#alzheimer's#epigenetics#h3k9me3#neurodegeneration#aging
