Boundaries of druggable targets are shifting
Advances in cell and gene therapies enable targeting of previously intractable biological mechanisms, necessitating a review of genomic profiling for drug discovery.
- Field
- cancer research
- What they did
- Researchers note that the boundaries of what is considered 'druggable' are expanding due to advances in cell and gene therapies, allowing consideration of previously overlooked genetic alterations in cancer treatment.
- Why it matters
- This provides drug developers with new reasons to revisit challenging targets and explore genomic alterations that were ignored when fewer treatment options were available.
#cell therapy#gene therapy#drug discovery#genomic profiling#cancer treatment



