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Boundaries of druggable targets are shifting

Advances in cell and gene therapies enable targeting of previously intractable biological mechanisms, necessitating a review of genomic profiling for drug discovery.

Field
cancer research
What they did
Researchers note that the boundaries of what is considered 'druggable' are expanding due to advances in cell and gene therapies, allowing consideration of previously overlooked genetic alterations in cancer treatment.
Why it matters
This provides drug developers with new reasons to revisit challenging targets and explore genomic alterations that were ignored when fewer treatment options were available.
#cell therapy#gene therapy#drug discovery#genomic profiling#cancer treatment

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