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Mice using SR-17018 do not develop high tolerance to the chemical

Laura Bohn's team demonstrated that compound SR-17018 relieves pain in mice without respiratory depression and enables morphine-dependent mice to reset tolerance without withdrawal symptoms.

Field
drugs and trials
What they did
Researchers developed a compound called SR-17018 that relieves pain in mice without causing respiratory depression and allows resetting opioid tolerance without withdrawal symptoms.
Why it matters
This could help people dependent on opioids reduce the risk of fatal breathing cessation and ease the process of treating withdrawal.
#opioid#sr-17018#tolerance#pain relief#withdrawal

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