RealFeedApp Steroids cause more exhausted T cells than alcohol
Single-cell RNA sequencing revealed that steroids cause T-cell exhaustion and neutrophilia, unlike alcohol.
- Field
- genetics and genomes
- What they did
- Researchers used single-cell RNA sequencing to compare bone tissue from patients with osteonecrosis caused by steroids, alcohol, or osteoarthritis.
- Why it matters
- This will help understand the differences in immune response and disease progression to develop better treatments for steroid-induced osteonecrosis.
#osteonecrosis#single-cell sequencing#steroids#t-cells#neutrophils
