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Senescent cells accumulate in tissues

The study found that the MTR4 gene slows cellular senescence in mammalian blood vessels and extends lifespan in nematodes by suppressing inflammatory signals from senescent cells.

Field
ageing and longevity
What they did
Researchers discovered that the protein MTR4 reduces cellular senescence in blood vessels of mammals and extends life in nematode worms.
Why it matters
This could help understand aging mechanisms in blood vessels and find ways to slow down the accumulation of senescent cells that cause inflammation.
#senescence#mtr4#vascular#nematode#longevity

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