RealFeedApp Neurons with multiple copy number variants are removed
Scientists from Harvard Medical School and Boston Children's Hospital found that neurons with multiple copy number variants are selectively eliminated around birth because these genomic alterations disrupt their ability to form synapses.
- Field
- the brain and neuroscience
- What they did
- Scientists discovered that during brain development, neurons with abnormal gene copy numbers (duplications or deletions) are eliminated because these changes prevent them from forming synapses.
- Why it matters
- This knowledge is important because such genetic alterations can affect brain function and may contribute to neuropsychiatric conditions.
#neurogenesis#copy number variants#synapse formation#perinatal elimination#genomic data
