RealFeedApp SynBITE removes unwanted cells while organ tissue is still forming
Researchers from the University of Pittsburgh developed the SynBITE genetic circuit to trigger programmed cell death in organoids. The method eliminates unwanted cells without damaging the vascular network, unlike traditional sorting techniques.
- Field
- ageing and longevity
- What they did
- Researchers developed a genetic system called SynBITE that allows the removal of unwanted cells from forming tissues, mimicking natural cell death.
- Why it matters
- This solution helps fix defective structures in tissue models (organoids) that previously became non-viable due to excess cells, and may accelerate the creation of functional organs for transplantation.
#synthetic biology#organoids#apoptosis#gene circuit#tissue engineering
