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- Borzoi-SE identifies functional hierarchy of super-enhancers across 90 human lineages
The Borzoi-SE framework predicted the functional hierarchy of super-enhancers across 90 human lineages, identifying hypersensitive site 2 as the dominant element.
- Field
- genetics and genomes
- What they did
- Researchers developed the Borzoi-SE algorithm to identify super-enhancers in DNA using only the genetic sequence, without needing additional lab tests.
- Why it matters
- This allows studying gene regulation in cells that were previously untested and accurately determines which DNA regions control specific cell types.
#super-enhancer#borzoi-se#genomic transformer#gene regulation#human lineages
