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Top science & technology news, August 13, 2026
- Decay of the Lef1-Srsf3-microRNA axis impairs DNA damage response and underlies stem cell aging
The decay of the Lef1-Srsf3-microRNA axis leads to impaired DNA damage response, contributing to stem cell aging.
- Accelerating GPT-5.6 Sol with Ultrafast Mode
Cerebras and OpenAI have launched a new service tier called Ultrafast Mode for the OpenAI API, powered by Cerebras. This mode allows GPT-5.6 Sol to generate up to 750 output tokens per second without compromising quality.
- PBS could lose 70 years of archives due to cloud vendor's failure
Without a backup, PBS is at risk of losing over 70 years of archival materials and programming after its contracted cloud storage vendor has apparently gone out of business.
- Targeting CDC42 with CASIN reprograms cell type-specific transcriptomes and MAPK-driven transcription factor networks in the aging brain
We found that targeting CDC42 with CASIN can reprogram cell-type specific gene expression patterns and transcriptional networks driven by the MAPK cascade in the aged brain.
- Toddlers' Tragic Death from Brain-Destroying Amoeba
A healthy toddler in Washington state fell ill suddenly. It began with vomiting, lethargy, and weakness on his right side. Then it progressed to a headache, fever, and trouble swallowing. At one point, he briefly became unresponsive, and he had episodes where he stopped breathing.
- Inflammaging and precision psychiatry: metabolic-immune crosstalk as a driver of late-life depression trajectories
Researchers propose that inflammation and metabolism interact to drive the trajectory of late-life depression.
- Hamilton-Zero: Foundation Model for Ground States of Arbitrary Quadratic Qubit Hamiltonians
The arXiv quant-ph archive announces a foundation model based on neural tensor networks for computing ground states of arbitrary quadratic qubit Hamiltonians. We demonstrate that this problem can be effectively amortized across an arbitrary and universal set of Hamiltonians by a foundation model with ~0.5B variational parameters, trained with contemporary techniques from large language models and deep reinforcement learning.
- Effects of dopamine and serotonin on persistence for delayed rewards in humans
People often must decide how long to continue waiting for rewards that will arrive at an uncertain time in the future. We propose that these persistence decisions involve weighing the benefits of continued waiting against opportunity costs of waiting, a balance that may shift over time. This framework suggests that persistence decisions share neural mechanisms with foraging decisions, which require ongoing comparisons between a current resource and possible alternatives. Dopamine and serotonin have been proposed to play opposing roles in foraging, with dopamine promoting exploration and seroto
- Nova-Quantum – Bare-Metal LLM Kernel (41 MB ISO, Booted Without OS)
Researchers have released a new version of the Nova-Quantum bare-metal Large Language Model (LLM) kernel that boots without an operating system. This could revolutionize how LLMs are developed and used.
- NVIDIA’s New $500B Plan for Aging GPUs is Risky but Brilliant
NVIDIA announced a plan to invest up to $500 billion in AI data centers. The key feature is creating a secondary market for aging GPUs, which will be guaranteed by NVIDIA with its own funds.
- The Nova Protocol: A Comprehensive Multimodal Longitudinal Study among Civilian Survivors of a Mass Trauma Event
The study examined the psychological and environmental factors affecting survivors of a mass trauma event at the Nova music festival in southern Israel, where over 370 attendees died.
- Anthropic Releases AI Agents to Battle Each Other
In a new research by Anthropic’s Frontier Red Team, it was observed that when groups of AI agents encounter each other in the wild, things get messy fast. This provides insights into potential risks as companies and governments move towards implementing autonomous agents across shared codebases.
- Quantum-limited imaging using diffractive optical neural networks
The arXiv quant-ph archive announces a method for quantum-limited imaging. We introduce an architecture for a measurement apparatus based on diffractive optical neural networks and photon counting that saturates this bound.
- Examples for use of AI and especially LLMs in major mathematical developments
Collection of examples where large language models (LLMs) like ChatGPT have led to major mathematical developments.
- PTC Therapeutics Wins $211M Auction for Sangamo’s Fabry Disease Program
Pharmaceutical company PTC Therapeutics has won a $211 million auction for Sangamo Therapeutics' program treating Fabry disease, outbidding Astellas and TerSera Therapeutics.
- Zealand sells its rights to Takeda’s blood cancer drug for $100M ahead of FDA approval decision
Zealand Pharma has sold its rights to Takeda's blood cancer drug rusfertide for $100 million before the FDA decides whether to approve it.
- AI isn’t ready to research itself
An agentic system successfully developed concepts from two computer-science papers — but the original authors were not impressed.
- DNA-GUARD: Molecular Access Control as a Physical Security Layer for DNA Data Storage
This study introduces DNA-GUARD, a molecular-level access control system that physically restricts data retrieval from DNA-encoded information rather than relying on computational encryption.
- Feasibility of Managing Diabetes Patients Identified Through Community Screening in Rural Ethiopia
A feasibility study at a primary healthcare facility in rural Ethiopia demonstrated the potential for managing diabetes patients using WHO PEN approach after community screening.
- Aging's largest natural experiment comes into focus
The GeroSCORE study, funded by the NIH, will investigate how sex, menopause, environment and life experience shape aging across the lifespan. Women outlive men in almost every country on Earth.
