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Top science & technology news, July 23, 2026
- Midlife Brain Aging Linked to Immune Cell Remodeling and Blood-Brain Barrier Decline
An analysis of aging human brains revealed widespread immune remodeling, blood-brain barrier deterioration, and genome architecture changes, challenging long-held assumptions about how the brain's resident immune cells are maintained.
- Coral Guard substrates accelerate growth and fragment fusion for coral restoration
The bioRxiv study on Coral Guard substrates evaluates their performance in long-term in situ coral nursery conditions. Fusion Guard Tiles, a geometry-optimized design, accelerates microfragment fusion.
- Autism-Like Traits in Mice Improved After Single Rapamycin Dose
A single dose of the immunosuppressive drug rapamycin improved autism-like traits in mice, suggesting a potential for rapid and temporary reversal of these effects in adulthood.
- If Scrubs Hurt, Your ZFS Design Is Broken
If scrubs noticeably impact production, it's a sign your storage design lacks the IOPS and headroom needed for routine maintenance.
- Glue Bonds to Nonstick Surfaces and Wipes Clean with Ethanol
Materials scientists are searching for an adhesive that can bond strongly to diverse surfaces and be easily removed and reused. Conventional polymers like epoxies achieve high strength through rigid, cross-linked networks but are brittle and prone to catastrophic failure under stress.
- Povorcitinib for hidradenitis suppurativa: Results of Two Pivotal Clinical Trials
Two pivotal clinical trials have shown that the oral JAK1 inhibitor povorcitinib significantly reduced abscesses and inflammatory nodules in patients with hidradenitis suppurativa.
- 'Make America Healthy Again': How Does It Stack Up Against Scientific Scrutiny?
Researchers discuss how well this health policy aligns with scientific research on topics such as vaccines and nutrition.
- Is personalized nutrition worth it?
Experts argue that the smartest health strategy may be simple: test first, then supplement second. Personalized nutrition is often seen as a quick fix for various health issues.
- Menopause telehealth leader Winona launches menopause supplement line
Winona, a physician-led telehealth company focused on menopause and perimenopause care, has launched a branded line of supplements to support women across the menopause transition. The products are intended to complement hormone replacement therapy or provide support for women who are not ready for HRT or who do not […].
- Programming Protein Shape via CAD Blueprints and Diffusion Models
Researchers have developed a method to program the global shape of proteins using computer-aided design (CAD) blueprints and diffusion models, advancing biotechnological applications.
- This El Niño is set to be the largest on record by a ‘mind-blowing margin’
Forecasters predict that the monster climate pattern will combine with global warming to push global temperatures in 2027 to new heights.
- A View of Aging Centered Around the Role of Karyopherins and Nuclear Transport
The biochemistry of aging is enormously complex, and it is very hard to pick apart which changes are definitively cause versus effect, and which changes are definitively more important than others. The only robust approach is to build a therapy that fixes just one change in isolation, and observe the results. This is not always possible or practical. When it can be done, a great deal is learned, however.
- Reviewing Age-Related Changes in Microglia
Microglia are innate immune cells residing in the brain, analogous to macrophages elsewhere in the body. Like macrophages, microglia are deeply involved in tissue maintenance as well as defense against pathogens and destruction of potentially cancerous, malfunctioning cells. Microglia adopt different packages of behaviors, called polarizations. In an aged tissue environment, microglia have a greater tendency to adopt an inflammatory polarization focused on defense rather than an anti-inflammatory polarization that aids in tissue maintenance.
- Supercooled Kidneys Transplanted into Pigs: A Landmark Achievement
Supercooled kidneys have been transplanted into pigs in a 'landmark achievement'. Kidneys kept at subzero temperatures can be stored for days before transplantation, raising hopes for longer-term storage of donated human organs.
- A highly penetrant LMNA R541C variant associated with dilated cardiomyopathy leads to dysregulation in metabolism and proliferation pathways in stem cell-derived cardiomyocytes
The bioRxiv study reveals that the LMNA R541C variant, which is highly penetrant, leads to metabolic and proliferative pathway dysregulation in stem cell-derived cardiomyocytes (iCMs).
- Genome Size Rather than Sociality Predicts the Turnover of Duplicated Genes in Termites and Hymenopterans
We studied the paranomes (the whole set of paralogous genes in a genome) of Blattodea and Hymenoptera, showing that regardless of sociality, duplicated genes turnover at similar rates.
- Early detection of Alzheimer’s disease with circular RNA from blood
We show that a blood-based circular RNA signature can accurately detect Alzheimer's disease as well as, or better than, current biomarkers and even predict who will develop symptoms before they appear.
- How AI helps scientists design the next generation of medicines
Designing and developing a new medicine is an expensive, failure-prone scientific challenge. A new drug can take many years to develop, at the cost of a significant investment. And even then, most possible candidates never reach the patient. For biologic medicines, therapies made from engineered proteins rather than synthetic chemistry (which are often used to treat diseases) are often more complex and costly.
- Ray tracing of massive amounts of animated geometry using tetrahedral cages
AMD FidelityFX™ Hybrid Shadows sample. This sample demonstrates how to combine ray traced shadows and rasterized shadow maps together for high quality and performance. Ray tracing has become a practical part of real-time graphics, but animated geometry still presents a difficult scaling problem. The paper 'Ray Tracing Massive Amounts of Animated Geometry' by Gruen et al., winner of the third-place Wolfgang Straßer Award (Best Paper) at High-Performance Graphics 2026, tackles a common production case: scenes with many complex objects that all deform differently.
- First US patient enrolled in clinical trial for new dry AMD vision treatment
i-Lumen Scientific announced that the first U.S. patient was randomized in the i-SIGHT2 pivotal study evaluating the i-Lumen AMD System for intermediate to advanced dry age-related macular degeneration.
