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New mechanism via SIRT1 activity

Researchers developed a senostatic treatment that reduces the rate at which cells become senescent in aged tissues. The approach modulates SIRT1 activity to enhance autophagy.

Field
ageing and longevity
What they did
Researchers developed a treatment that slows down the aging of cells in aged tissues, allowing the immune system to clear them more effectively.
Why it matters
This approach could reduce the overall burden of senescent cells over time, though it remains unproven whether it prevents necessary aging in processes like wound healing.
#senescence#sirt1#usp25#senostatics#autophagy

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