New workflow detects trace cancer DNA in plasma samples
The new duplex chemistry workflow detects trace circulating tumor DNA (ctDNA) by confirming base calls on complementary strands. Kits are expected to ship in Q1 2027.
- Field
- tools and releases
- What they did
- Illumina has made available a research-only sequencing workflow based on duplex chemistry, which verifies each base by checking both complementary DNA strands.
- Why it matters
- This approach increases confidence in detecting trace amounts of circulating tumor DNA in blood, which is essential for monitoring residual disease after cancer treatment.
#duplex sequencing#mrd#ctdna#illumina#genomics



