RealFeedApp Lysosomes become dysfunctional with age
Researchers developed a model showing how accumulated undigested proteins cause lysosome dysfunction and cell death. This process triggers inflammation and shortens organism lifespan.
- Field
- ageing and longevity
- What they did
- Researchers developed a 'lysosomal aging clock' and identified a new biomarker linking lysosomal dysfunction to aging.
- Why it matters
- This could help understand the mechanisms of cellular aging and develop methods to combat age-related diseases.
#lysosomes#aging#autophagy#senescence#inflammation
