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Probiotics lower plasma pTau181 levels

A clinical trial showed that older adults with early cognitive impairment who took multistrain probiotics for six months saw improved cognitive test scores and reduced plasma pTau181 levels.

Field
medicine and diagnostics
What they did
Researchers conducted a clinical trial where older adults with early signs of cognitive impairment took multistrain probiotic supplements for about six months. Participants taking probiotics showed better results on cognitive tests compared to the placebo group and experienced a significant reduction in pTau181 levels in their blood.
Why it matters
pTau181 is a blood-based biomarker for Alzheimer's disease, as elevated levels in the blood often precede dementia symptoms and reflect changes occurring in the brain.
#probiotics#cognitive decline#ptau181#alzheimer's#clinical trial

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