Platform visualizes RNA dynamics with single-transcript-level sensitivityResearchers developed a high-signal RNA imaging platform coupling CRISPR-dCas13X with binding-dependent fluorescence stabilization. The system enabled precise visualization of endogenous mRNA dynamics in living plant cells with minimal perturbation.
PLOS BiologyBiotech
- Field
- tools and releases
- What they did
- Researchers developed a CRISPR/dCas13X-based imaging system that uses a specific signal to stabilize RNA molecules within plant cells.
- Why it matters
- This enables precise tracking of individual RNA molecules and their movement in living plants while minimizing background noise.
#crispr#dcas13x#rna imaging#plant biology#single-molecule
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