Testing on a single RTX 3090 showed Ollama loses to LM Studio in speed and load times, but wins on simplicity for always-on servers. Both tools use the same Qwen3.5 GGUF file, yet LM Studio provides faster model access.
The project now enables running multi-modal LLMs across various hardware, from consumer machines to enterprise servers. Developers emphasize the stability of the API for the local AI ecosystem.
An ex-OpenAI engineer reported that Chinese AI labs are training models on Nvidia Blackwell chips despite export restrictions.
Researchers demonstrated that GPT-6-Astra can fix errors in Qwen3.5-0.8B by modifying just 0.016% of its weights without gradients. The new dspy-wsp tool extends this weight-space programming to decision models.
From 2023 to 2025, startups focused on the central nervous system raised $1.9 billion from 26 venture firms. In mid-November 2026, London-based Oyster Therapeutics raised $60 million in a Series A round.
Researchers introduced an unbiased method to quantify stoichiometric relationships between catabolism and anabolism in genome-scale metabolic models. Comparing catabolic strategies across diverse microbial species revealed that networks vary based on energy and carbon sources.
The author analyzed the JEPA architecture, where an encoder converts frames into compact learned embeddings. A predictor forecasts the next state given an action, and a planner selects sequences that minimize the distance between the predicted end state and the goal embedding.
Women over 30 can now access personalized aging tests previously available only to men. The solution allows tracking biological aging in women using the same metrics as men.
The company develops peptide therapeutics for metabolic disorders and fibrosis using proprietary delivery technologies. The lead candidate is in Phase 2 for treating metabolic dysfunction-associated steatohepatitis.
Researchers at PPPL developed a new method to predict qubit behavior in diamonds more quickly and accurately. This breakthrough paves the way for quantum computers and sensors operating at room temperature.
Researchers developed the HandShake predictor, which uses only sequences to predict protein binding interfaces. The model was trained on the large PPInterface dataset and employs a LoRA mechanism.
Researchers used temporal interference stimulation to activate the hippocampus in 64 healthy adults. The method proved the causal link between this structure and rapid motor sequence learning.
Researchers describe a mechanism where one neural network can induce harmful behavior in another by directly modifying its weights, comparing this to prion disease. Defense against such interference is deemed practically impossible due to the asymmetry between creating an attack and searching for it in the weight space.
Researchers benchmarked dLbCas12a and denAsCas12a effectors, demonstrating that the T-rich PAM system expands promoter access and facilitates multiplexed regulation.
Researchers found that brain structure-function coupling strengthens during movie watching and weakens during working memory tasks. Older adults showed reduced coupling in auditory and somatomotor regions.
Researchers used chromosome-level genomics and cross-species enzyme screening to boost bakuchiol yields in Yarrowia lipolytica. Deleting 40 N-terminal amino acids from the PcPT6 enzyme raised production by 53% compared to the full-length version.
Venture capitalists in Israel are monitoring the fallout from Jensen Huang's resignation, noting that Nvidia remains central to Israel's economic growth and serves as a hub for numerous local startups.
The $875 million SMART system rerouted 180 flights, saving 10 minutes and 80 gallons of fuel per flight. The labor union representing controllers did not participate in designing or testing the system.
OpenAI introduced a feature enabling Dot agents to make purchases on behalf of users, requiring approval via Face ID or fingerprint.
A review of 361 studies found evidence that lower protein intake may slow biological aging, though protein remains essential for muscle repair and immunity.