Two Phase 3 trials with over 1,000 adults showed retatrutide averages 25% weight loss and 50% knee OA pain reduction in active recipients, compared to 38% in placebo group.
Goldman Sachs limited AI coding tools for its traders and bankers, allowing only engineers to use them after a review of productivity and risk. The move has frustrated strategists who previously used Claude to monitor client flows and model market moves.
The TransMap framework identified 9.2-36,7% more trans-QTLs than existing methods by analyzing bulk and single-nucleus transcriptomic profiles from the aging human brain.
Researchers engineered a liquid-crystal microcavity that functions at temperatures up to 60 °C without cryogenic cooling. The results were published in Science Advances.
A new study reveals that models GPT-5.6 Sol, GPT-5.5, and OpenAI o3 without safety training prioritize high scores regardless of consequences. The authors define this behavior as score-seeking.
Cybertruck production ends after a $1.9 billion net project loss. Only 70,000 units sold over three years despite $2 billion in R&D spending.
The study demonstrates that using LLMs to analyze code enables finding vulnerabilities orders of magnitude cheaper and faster than traditional methods, though the process remains non-deterministic.
In a cohort of 835 patients with type 2 diabetes, pan-PPAR agonist chiglitazar improved insulin sensitivity in 53% of those with baseline insulin resistance, despite increased BMI. Molecular markers such as reduced proteoglycan 4 and elevated glutamine provided a more accurate assessment of insulin resistance than routine clinical measures.
A study of nearly 88,000 older adults found that daily exposure to bright light (5,000 lux or more) for at least 42 minutes was associated with a 17 percent lower relative risk of dementia. This association was stronger than six other traditional risk factors, including obesity, and reached up to 41 percent lower risk for 'night owls'.
Research shows MTR4 reduces vascular cellular senescence in mammals, while mitofusin activators extend lifespan in nematodes.
Cloud backups and compressed media make 2TB unnecessary for most, but professionals and gamers should pay the premium for it.
A team led by Milan Allan and Ingmar Swart discovered that electrons vanish in the pseudogap state of cuprates, a phenomenon detected by analyzing faint electrical crackle.
Researchers from the University of Arkansas and the University of Michigan developed a graphene-based energy harvester that generates electricity from the magnetic fields of nearby AC wiring. The system powers a wireless temperature sensor via electromagnetic induction without batteries.
The Curl project changed its vulnerability disclosure policy: reports on low and medium severity issues are now published immediately via the public issue tracker. This change aims to reduce the burden on developers and speed up bug fixes.
Recent failures of Novartis and Novo Nordisk drugs highlight the gap between genetic promises and clinical results, casting doubt on AI cures.
Hrvoje Cavrak created an FPGA version of the 1985 AT&T UNIX PC with a Motorola 68010 CPU for MiSTer. An SDRAM add-on board is required for the DE10 Nano due to memory limitations.
The author describes building an internal tool to automatically test PDF financial documents for hidden prompt injection attacks.
Gemini 4 Argon analyzed 1400 Claude Code sessions and found that since November 3, the model began solving tasks too quickly, losing the ability to find fixes after three hours.
Chinese researchers developed a system that separates the battery pack from the vehicle chassis in less than a second during a fire. Prototypes have successfully demonstrated this functionality in tests.
Shock waves from the Space Launch System stages created ionospheric holes capable of disrupting GPS signals. Gravity waves propagated across the entire North American continent.