The agency issued final guidance requiring manufacturers to implement a potency assurance strategy across the entire lifecycle of cell and gene therapy products to ensure batch consistency before patient delivery.
The AI agent selected the drug, identified brain coordinates, and injected 250 nanolitres while a vet monitored irreversible steps.
The study found that the availability of resistance mutations negatively impacts the fitness advantage of CRISPR immunity in Pseudomonas aeruginosa. This effect varies predictably across different virulent phages.
Researchers found that the human ventromedial prefrontal cortex uses hexadirectional modulation to represent affective space, confirming the abstract nature of emotion concepts.
According to IPO filings, the cost of internal Claude usage at retail prices surpassed total employee compensation by September. Over 90% of the code added in September was written by Claude.
The SWIMR statistical framework combines multiple scRNA-seq references while accounting for spatial correlations, enhancing deconvolution accuracy in complex tissues compared to single-reference methods.
Creators of Momentic use autonomous agents to plan and test web, iOS, and Android applications. DeepSWE v1.1 research showed Sonnet 5.5 achieved a 66.2% pass rate when banned from writing tests, compared to 65.3% when allowed.
Scientists from UC Santa Cruz demonstrated that psilocybin increases dendritic spine volume and development in mice within 24 hours without inducing trip-like sensations.
Seven unrelated carriers harbored the same BRCA1 frameshift variant, representing 22% of all pathogenic variant carriers in the cohort. Haplotype analysis confirmed a common founder origin within a shared ancestral block of approximately 581 kb.
10x Genomics launched Sentira Single Cell, a cloud-based agentic analysis tool powered by Anthropic's Claude models. Researchers who previously spent weeks on analysis can now get results in hours.
The FDA accepted UniQure's marketing application for AMT-130 gene therapy targeting Huntington's disease, with an approval decision date set for May 1, 2027.
A Latus Bio study in Nature Communications demonstrates that inhibiting the MSH3 protein can reduce somatic DNA instability and extend lifespan by decades.
A study from the University of Pittsburgh found that shared inflammatory processes cause cognitive decline in pulmonary hypertension patients, suggesting broader implications for vascular diseases.
New benchmark Realtime-Bench reveals that modern language models perform poorly on tasks requiring immediate decisions. Researchers from the University of Texas at Austin, Ohio State University, University of Illinois at Urbana-Champaign, NVIDIA, Northwestern University, and Steadyworks developed a suite of 50 interactive tasks to evaluate AI response times.
Researchers Steven Austad and Arlan Richardson explain why traditional rodent models are insufficient for understanding aging and what unexpected species might reveal.
Janis Hesse's study on macaques reveals a rhythm linking frontal and posterior brain regions during conscious perception.
The company is exploring a deal with EchoStar to access terrestrial networks and build a hybrid cellular-satellite system. This move aims to help SpaceX compete with AT&T, T-Mobile, and Verizon by improving indoor coverage.
Researchers introduced a framework where a single model generates register-transfer-level code, performs EDA checks, and revises implementations. The approach employs Pattern-Aware Policy Optimization (PAPO) to reinforce concise successful corrections.
A coding model automatically reconfigures robot control based on failure analysis, achieving a 4.5x performance increase on unseen scenes.
Andreessen Horowitz and DFJ Growth co-led the round. Bridgit Mendler leads the satellite communication startup.