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Top science & technology news, October 13, 2026
- Unsloth speeds up UI by up to 10 times
Unsloth library increased training and inference performance by up to 10x, introducing browser script execution and improved file handling. The update supports LTX-2.5 video generation, Wan2.2 image-to-video, and faster LoRA training with optimized hardware compatibility.
- PrimeStack achieves precise integration of large DNA sequences in rice plants
The PrimeStack platform combines prime editors with serine integrase Bxb1 to achieve precise, site-specific integration of large DNA sequences in rice without DNA breaks. Targeted integration efficiency reached 45% based on junction-specific PCR analysis.
- Dynamic virtual GPU cloud Minions runs workloads on idle Apple Silicon
The system dynamically pools unused Apple Silicon GPUs across macOS devices to run large-scale machine learning workloads without new hardware purchases.
- A 9B model achieved inference on 8 of 9 tested hardware types
Experiments suggest 9B models can run on 8 of 9 tested IoT hardware types, while 30B+ models achieve end-to-end replication. A self-replicating agent on devices like smart ovens could operate autonomously without a centralized shutdown point, potentially doubling in days.
- Skmer estimates θ using k-mer sets
The DipSkmer method analyzes the population-scaled mutation parameter θ by computing k-mer sets, avoiding the need for genome assembly. This enables tracking population health and dynamics with high accuracy at low cost.
- Deal value potentially exceeds $250 million
Boehringer Ingelheim and Variant Bio signed a deal potentially exceeding $250 million to use AI for discovering new drug targets for heart disease.
- Nvidia found $1B under the couch to secure computing
Researchers warn that Chinese models can execute infrastructure attacks while defenses remain unprepared. Meanwhile, Nvidia allocated $1 billion to secure US scientific computing dominance.
- Rubedo Life Sciences reports 2.1-year reduction in skin epigenetic age
In a Phase 1b trial with 11 pairs of photoaged skin samples from atopic dermatitis patients, 4 weeks of RLS-1496 treatment yielded a statistically significant mean reduction of 2.1 years in epigenetic age (p=0.032). The best responder showed an 11.7-year reduction at Day 63, accompanied by a 10% increase in type III collagen fibers on histology.
- SWE-bench: $1000 compute training reaches 11.0% pass@1
Researchers trained coding agents from scratch with only $1,000 in compute, achieving an 11.0% pass@1 rate on SWE-bench. This performance matches Claude 3 and exceeds results from models trained on minimal budgets.
- xNNDriver quantified signal strength for 3 008 candidate genes
Researchers introduced two interpretable neural network frameworks linking cancer mutations to genome-wide DepMap gene dependencies and drug-response patterns. The models quantify driver potential by evaluating the strength of the mutation-dependency signal and prioritizing genes with broad functional footprints.
- llama.cpp updated to version b11521
The update includes updating llama.cpp for decision models and optimizing recurrent state in MLX.
- Laplace tests physical AI systems to ensure they do not fail
Laplace Intelligence is building automated red-teaming for robotics to identify failure points before physical AI enters the real world. CEO Howie Sun aims to create a shared evidence foundation to build trust with customers, insurers, and regulators.
- Satlyt raised $8 million in seed funding
The engineer, formerly at Google and SpaceX, founded Satlyt to enable satellites to share large computing jobs. The company raised an $8 million seed round to launch its software on a SpaceX rocket.
- Sequential sampling during encoding depends on cognitive demand
Researchers found that gaze patterns spontaneously align items into a sequence to reduce memory load. Under high demand (4 items), encoding-based organization breaks down, and the brain relies on revisiting items during maintenance.
- Small models with up to 360 million parameters run in the browser
The "ask my blog" system uses a local model to summarize text found in a 4 MB lookup table, keeping all data on the user's device. Testing revealed that small models often generate inaccurate content.
- Autism is diagnosed four times more often in boys than girls
Researchers from Baylor College of Medicine found that noncoding variants of the MECP2 gene on the X chromosome may account for the fourfold higher diagnosis rate of autism in males compared to females.
- Clinical trials for CAR T-cell therapies halted
Shares of CRISPR genome-editing firm Caribou fell 62% after announcing workforce reductions and pausing trials for two allogeneic CAR-T therapies. The company's staff numbered 97 people as of February 27.
- Long-read sequencing added clinical value in 24.8% of cases
Sweden has established a national ecosystem integrating population genomics and rare disease diagnostics. Long-read genome sequencing enabled molecular diagnoses for 33.2% of patients and avoided 42 follow-up analyses.
- Global availability of Gemini 4 Argon for developers and enterprises
The new Gemini 4 Argon model is now available via API and ranks #1 on the Vals Index for finance, coding, and legal tasks. Pricing starts at $2 per million input tokens and $10 per million output tokens.
- Gut microbiome changes begin as early as mid-30s
A review of human studies indicates that the gut microbiome begins to change significantly as early as the mid-30s, replacing beneficial microbes with pro-inflammatory ones.
