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Top science & technology news, October 9, 2026
- We set a new record for n=11
Researchers used LLMs to evolve programs, updating records for square packing including the optimal solution for n=11. The approach involved seeding primitives with Claude and conducting evolutionary search.
- Black Lotus Labs® disrupted the PoeLLM campaign
The PoeLLM campaign uses a GitHub-hosted poem to dynamically locate command-and-control servers for infected systems. Researchers from Black Lotus Labs® identified vulnerabilities in open services like LiteLLM and Ollama, successfully disrupting the threat and protecting Lumen Defender® customers.
- Study of 12.4 million immune cells reveals determinants of immune aging
A study of 2,600 individuals found that the ratio of GZMK+ to GZMB+ T cells predicts health outcomes. Genetic and environmental factors drive differences in immune aging between people of the same age.
- Accrua platform launches in the US in October 2026
Accrua by Deep Longevity uses an AI model to identify 'fast agers' via blood tests and directs them to GLP-1 treatments. The US telehealth platform is scheduled to launch in October 2026.
- Phosphate depletion restores Mtb growth on lactate
Mycobacterium tuberculosis stops growing in acidic conditions when supplied with lactate if it cannot import phosphate. The combination of lactate and phosphate drops intracellular pH below 6.7, while a phosphate transporter mutant maintains a cytoplasmic pH above 7.2.
- CONCORD platform encodes 45 689 bits into DNA
Researchers developed the CONCORD platform combining conjugation and base editing to write data directly into living cells. The system successfully encoded 45,689 bits of information, including artifacts from NASA missions.
- Python 3.15.0 released on Oct. 9, 2026
The 3.15.0 release includes 5,643 commits from 1,012 contributors, featuring a JIT compiler with 7–12% speedup and new types like sentinel and frozendict.
- Tiny Health tests more adults than babies
The Austin-based company completed an oversubscribed Series B round led by B Capital, totaling $46 million in funding. Adults now outnumber babies in its testing volume using shotgun metagenomic sequencing.
- Each 1-SD decrease in LC linked to increased pTau217 levels
A study of 163 healthy older adults found that lower MRI intensity in the locus coeruleus correlates with higher plasma pTau217 levels. This links neuroimaging biomarkers to blood-based markers for detecting early Alzheimer's disease.
- Nine evolution rounds track trajectory toward new activity
Researchers used directed evolution to create variant E5, capable of reverse transcribing RNA with 2'-modifications, an activity previously inaccessible to this enzyme.
- Microsoft-Decision-1 outperforms LLMs on structured decision tasks
The new Microsoft-Decision-1 model is purpose-built for structured tasks like routing, classification, and verification, delivering high performance with low latency. It outperforms language models and other decision systems in structured decision tasks while integrating securely into existing applications and agents.
- SpaceX approved to launch 15 000 satellites
SpaceX secured licenses for 14 MHz in the 800 MHz band from Grain Management, covering approximately 100% of the US population to fill technical gaps for its terrestrial mobile network.
- Model shows reserve workers enhance foraging efficiency
The study found that departure and return rates of foragers regulate the colony's energy balance. Simulations based on data from four Aphaenogaster senilis colonies confirmed the adaptability of this strategy.
- Average Bell pair generation rate reaches 1.03 kHz
Researchers entangled a barium ion with a silicon-vacancy center in a diamond with 87.9% fidelity and a rate of 1.03 kHz, four times faster than prior photonic links.
- Two DNA-recording systems reconstructed mouse cell family trees
The team led by Jay Shendure and Chengxiang Qiu developed DNA Typewriter to reconstruct cellular lineages. Published in Science and Cell, the studies offer high-resolution views of mammalian development.
- Qudit error-correcting codes reach 10 percent error threshold
Researchers extended many-hypercube codes to qudits with dimension up to 13, showing the error threshold rising from 5.1 percent for qubits to 10 percent.
- Hydra architecture removed the U-net decoder
Replacing Borzoi transformer blocks with Hydra increased inference speed by 5.7-fold on 8,192-token inputs and improved eQTL classification accuracy. Linear cost allowed 32 bp resolution and removed the U-net decoder.
- Fractional anisotropy drops in older adults
Using NODDI and DTI on 86 cognitively normal adults, researchers found widespread reductions in fractional anisotropy and neurite density in older groups, linking these changes to cognitive domains.
- Amazon drops NDAs for data center government deals
Amazon will no longer use NDAs when negotiating data center agreements, aiming to reduce community opposition, though it remains unclear if this will build trust in AI infrastructure.
- Subcortical anatomy differs between sexes
Analysis of 2,886 participants revealed robust sex-based differences in subcortical brain structure that persist into adulthood and are established before puberty.
