AI can now generate images using editable code instead of text prompts. This project explores reinforcement learning in creative tasks by making code the editable artefact.
AI startup General Intuition, building a foundation model for generalized AI agents, is raising funds at a $6 billion pre-money valuation. New investors include Valor Equity Partners and Point72 Ventures, while existing ones like Khosla Ventures are also participating.
New method reduces false neuron counts by 37-46% in zebrafish brain recordings.
Paul Graham says he would learn to build LLMs from scratch at 17 instead of starting a startup. He believes deep understanding of LLMs leads to better startup ideas.
A 20-day randomized, placebo-controlled trial found that daily peppermint oil supplementation reduced systolic blood pressure by 8.48 mmHg in 40 individuals with pre- and stage 1 hypertension.
OpenAI is developing AI agents that can control users' digital lives, including email, Slack, phone, and more, raising questions about trust and control over such technologies.
Modified mRNAs encoding cell cycle regulators increased beta-cell numbers in rats by nearly 100%, but required co-delivery of MYC mRNA for human cells.
Microstructural changes in gray matter may support circuit refinement and mature behavior through interactions with functional circuitry.
Ox Alpha is a reasoning-first model capable of handling a million tokens of context.
Senescent cells accumulate with age throughout the body, either in response to forms of damage and stress or on reaching the Hayflick limit on replication. A senescent cell ceases to replicate, grows in size, and secretes a potent mix of pro-growth, pro-inflammatory signals. With age, the immune system becomes less efficient at clearing senescent cells. Signals from these cells can induce nearby cells to also become senescent, accelerating their accumulation.
Roche acquires a clinical-stage obesity drug from Hanmi targeting an underexplored mechanism, paying $190 million upfront.
The atlas contains 14,358 curated records of engineered genes and plant traits.
Genomic sequencing altered care trajectories in 53% of patients in Dubai's pediatric ICU.
Roche and Eli Lilly have received FDA clearance for their latest Alzheimer’s disease diagnostic, which is the first of its kind.
Injecting a person's own mitochondria into the retina was safe but had only a temporary effect on restoring vision.
The study found that epigenetic noise in human tissues is largely determined by replicative history rather than chronological age. Analysis of 1,531 samples from 14 tissues showed that corrected entropy was low in promoters and CpG islands, but high in CpG-poor and intergenic regions. Biological age acceleration was largely attributable to cell division in a tissue-specific manner.
Pacific Fusion is building a reactor near a US nuclear-weapons lab to leverage its expertise.
The study proposes DSTCL to estimate the causal effect of ABeta42 on cognitive outcomes in African Americans. It addresses small sample sizes and noise from irrelevant covariates. The work includes 1500 participants and 100,000 observations, but does not account for genetic factors.
The study shows that the gene femaleless (fle) plays a key role in female gametogenesis in Anophe, gambiae. Using gene drives with distinct temporal expression profiles, the researchers modulated Cas9 activity. The zpg-driven system achieved 98% transmission through males but caused complete sterility in hemizygous females due to early biallelic disruption of fle.
Researchers showed that mitochondrial supercomplexes play a key role in mitochondrial function and the rate of aging.