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Top science & technology news, August 21, 2026
- Early-life stress leaves a 'scar' inside brain cells in mice
A study found that early-life stress alters DNA packaging, leaving a molecular memory of trauma that makes the brain vulnerable to future stress.
- Chutes & Ladders—Neumora shuffles leadership ahead of IND
Joshua Pinto, Ph.D., has been appointed CEO of Neumora Therapeutics, a clinical-stage biotech with obesity and neuro assets.
- Personalized mRNA vaccine shows promise for cancer
Clinical trial of an mRNA vaccine against melanoma shows effectiveness. US NSF to issue lowest number of new grants in 40 years.
- Responsiveness of epigenetic aging biomarkers to longevity interventions in humans
A study evaluated the response of 16 epigenetic aging clocks to a range of pharmacological and lifestyle interventions across 51 longitudinal studies, highlighting their potential as reliable aging biomarkers.
- LFM2.5-DSpark: Up to 3.2x Faster Inference from H100 to Macbook
LFM2.5-DSpark achieves up to 3.2x faster inference with speculative decoding, without compromising output quality.
- Mesoscale medial temporal lobe connectivity patterns relate to tau pathology and memory in older adults
Research links mesoscale MTL connectivity patterns to tau pathology and memory decline in older adults.
- Defining a leptomeningeal blood cerebrospinal fluid barrier as a specialized vascular interface
Scientists identified the leptomeningeal vascular interface as a distinct endothelial population, different from the blood-brain barrier.
- New Narcolepsy Drug Could Unlock Host of Novel Brain Therapies
FDA-approved narcolepsy drug shows potential for broader neurological applications. Researchers also present the longest-lived human brain organoids yet.
- Starcloud raises $250 million for orbital data centers
Starcloud has secured an additional $250 million to expand manufacturing and advance its largest orbital data center spacecraft, Starcloud-3, intended for launch on SpaceX’s Starship.
- Top-selling NAD+ supplement Tru Niagen lands at GNC, Sam’s Club
Niagen Bioscience announced Tru Niagen is now available at nearly 300 GNC and Sam’s Club locations across 44 states and online. The GNC assortment includes Tru Niagen Beauty, the first U.S. beauty supplement with Niagen.
- Teaching a local LLM to reason about a new domain through continued pretraining
An experiment on how to train a local LLM to specialize in a new domain using continued pretraining.
- Mitochon receives $1m award for ALS phase 2 study
Mitochon Pharmaceuticals received a $1 million Hoffman ALS Clinical Trial Award to support a 24-week phase 2 study of sporadic ALS. The funding aims to expand on recent European clinical work showing rapid reduction in neurofilament light levels.
- Putting epigenetic aging clocks on trial
A new study tests whether DNA methylation clocks act as valid surrogate endpoints for aging, responding to real clinical benefits and remaining stable when there are none.
- From Models to Agents: The Next Phase of AI Adoption in Molecular Discovery
AI is being used in scientific research, but hasn't reached the breakthrough seen with 'Claude Code'. The compute power and models exist, but a coordination system is missing.
- TIMP2 Protein Therapy Favorably Adjusts the Behavior of Microglia in the Aging Brain
Therapy with TIMP2 protein improves microglia behavior in the aging brain, potentially slowing age-related changes.
- Towards General Embodied Intelligence: Integrating Large Language Models, Knowledge Bases, and Reasoning Capabilities to Build the Next Generation of AI Agents
The paper explores integrating large language models, knowledge bases, and reasoning capabilities to develop the next generation of embodied AI agents, emphasizing their logical, knowledge-based, and physical integration.
- Lab-Grown Neocortex Models Mimic Early Brain Organization
Scientists created lab-grown human organoids that mimic early brain development by using chemical signals to guide cells to adopt distinct regional identities.
- Resource-Efficient Bio-Molecular Docking on a NISQ-era Digital Quantum Computer
Researchers present a method for efficient bio-molecular docking on a NISQ-era quantum computer. The approach reformulates docking as a maximum vertex-weighted clique problem, enabling faster computations.
- Reinforcement Learning to Harness Approximation Errors for Long-Time Quantum Simulation
RL-Trotter treats approximation errors as resources for error correction, improving long-time quantum simulation accuracy through reinforcement learning.
- ChatGPT can now send texts for you with new Apple Messages plug-in
OpenAI has launched an Apple Messages plug-in for ChatGPT, allowing users to connect their Messages inbox with the chatbot. This enables sorting, analyzing, and editing messages directly from ChatGPT.
