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Top science & technology news, August 2, 2026
- Drug Reverses Autism-Like Brain Changes in Adult Mice Within Hours
Mice exposed to inflammation during pregnancy developed lasting autism-like brain and behavioral changes, suggesting that early inflammation can disrupt brain development into adulthood. A single dose of rapamycin rapidly improved several of these changes, including overactivity, seizure risk, sensory sensitivity, repetitive behaviors, and abnormal brain functional network organization.
- Prevent Cognitive Debt by Manually Retyping LLM-Generated Code
To avoid cognitive debt from using an AI coding assistant, it's recommended to manually retyping the code generated by these assistants. The author acknowledges that they use such tools on personal projects but finds them unsatisfying and disorienting.
- Kimi K3 on MI355X at Better Performance per Dollar Than B300
AMD continues to prove its case as the winner in performance per dollar with Kimi K3, a model promising Fable/Sol levels of intelligence. The new era for open source models is here.
- Minocycline Engages Microglia in the Midbrain Periaqueductal Grey to Attenuate Hypoxia-Triggered Panic-Like Behaviour in Rats
Previous studies have suggested that inflammatory processes may contribute to panic attacks. This study shows that minocycline can engage microglia in the midbrain periaqueductal grey and attenuate hypoxic-like panic behavior in rats.
- Kimi K3, Opus 5 and DeepSeek V4 Flash: LLMs on Baba Is You
This month saw the release of several exciting models: Kimi K3, Grok 4.5, Gemini 3.6 Flash, Claude Opus 5, and DeepSeek V4 Flash 0731. They are all reasonably high in the Artificial Analysis Intelligence Index (AAI). These models were tested on Baba Is Bench, where agents play the game Baba Is You.
- Fight Aging! Newsletter, August 3rd 2026
Fight Ager! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers.
- YC Founder Asks Desperate Job Seekers to Tattoo Themselves for an Interview
A San Francisco AI startup CEO is apologizing for asking people to permanently tattoo themselves in exchange for a job interview.
- Automating clinical trial outcome identification and misreporting detection using RegCheck
Objective To evaluate the accuracy and cost of RegCheck, an automated large language model (LLM)-based workflow, for identifying clinical trial outcomes and detecting outcome misreporting by comparing its outputs with manual assessments from the COMPare Trials project.
- Longitudinal Reorganization of Cortical and Cerebellar Functional Networks in Spinocerebellar Ataxia Type 7
Researchers investigated longitudinal changes in resting-state functional connectivity in patients with spinocerebellar ataxia type 7 (SCA7) and found lower MoCA and MMSE scores.
- A PRISMA-Aligned Agentic Framework for Medical Systematic Reviews and Evidence Synthesis
Medical systematic reviews are central to evidence-based medicine, but they remain slow, labor-intensive, and difficult to maintain under the full Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) workflow. Recent LLM-based deep research agents offer a promising route to addressing this challenge, yet reliable deployment in medical systematic reviews remains limited by insufficient clinical domain knowledge and inconsistent adherence to evidence-based methodological standards across the full workflow. We address these gaps with MedSR-Copilot, a PRISMA-aligned multi-agent system.
- I'm (mostly) picking models on speed now, not intelligence
For the first time in memory, I'm choosing my daily driver models based on their speed rather than raw intelligence.
- Malaysia Orders Shutdown of Balaji Srinivasan's Network School
Malaysian government orders the shutdown of a startup-centric community called the Network School, run by entrepreneur and investor Balaji Srinivasan.
- Inside the London Hacker House Taking a Stand Against Founder Burnout
Six twentysomethings in East London have built what they say is the anti-San Francisco hacker house. The goal is a 'holistic improvement in life,' rather than '12 weeks, Demo Day is coming.'
- Population-Scale Landscape of Mobile Element Insertions Across 82 Diverse Indian Populations
We characterized non-reference Alu and LINE1 insertions in 7,478 whole genomes from the GenomeIndia project representing 82 populations selected to capture India's genetic diversity.
- Prevalence of Chloroquine and Antifolate Drug Resistance Markers in Plasmodium falciparum Parasites in Rwanda, 2018
In Rwanda in 2018, prevalence of chloroquine and antifolate drug resistance markers was observed in Plasmodium falciparum parasites, highlighting the need for continuous molecular surveillance to maintain efficacy against malaria.
- v0.1.511-beta
Unsloth version 0.1.511-beta released with no additional details in the text.
- This Hi-Fi Tape Recorder Changed Radio Forever
A German engineer wanted a cheaper cigarette. The popular crooner Bing Crosby wanted a vacation. Satisfying both desires inadvertently led to the invention of the laugh track. Along the way there were Nazis, spoils of war, and more than one accidental encounter. Tying together this quirky history is the Magnetophon.
- São Paulo Resident Transforms Degraded Area into Urban Forest
A São Paulo resident transformed a degraded area into an urban forest, which became an important green corridor in the city's heart and provided shade and leisure for the population.
- Video2NAND – Abusing video codecs for great computational power
Abusing the prediction mechanisms of video codecs like VP8 to build arbitrary logic circuits, demonstrating a powerful computational system built from video data.
- Canadians are Leaving the Country at Record Levels. Can Anyone Solve This?
Data from a recent Hub analysis shows record emigration from Western countries, with roughly 4 million people leaving in 2024. The issue has sparked discussions and debates.
