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Top science & technology news, July 30, 2026
- You can't solve computer use by ignoring the interface
Computer use is far from solved. Right now, agent-based computer use is one of the biggest levers for real-world AI impact. LLM-based agents are transforming software development, but most intellectual work is gated behind using software. When coding agents are so good, it is natural to ask: can they file my taxes in a government portal, fix a text document, test a website?
- Florida Plans to Build Air Taxi Pads Using $200M Intended for EV Chargers
Florida is redirecting nearly $200 million in federal funding intended for electric vehicle charging infrastructure to build out an electric air taxi network, despite having fewer chargers per vehicle than the national average.
- Advancing the price-performance frontier with GPT‑5.6
OpenAI improved GPT-5.6's efficiency to offer it at lower prices and faster performance for various enterprise workloads.
- Commonwealth Fusion Systems Secures Another $1B
Commonwealth Fusion Systems (CFS) has raised an additional $1 billion in funding, solidifying its position as the best-funded fusion power startup. The company is currently building its demonstration reactor and finalizing plans.
- High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations
Two-photon calcium imaging is a standard tool for measuring neuronal population activity in vivo, yet how axial resolution, sensor expression strategy, and analysis pipeline jointly affect data accuracy remains poorly characterized. Here, we imaged the same L2/3 neurons in mouse primary visual cortex at five axial resolutions (3.6 - 21.0 m), spanning current two-photon systems from benchtop microscopes to large-field-of-view and miniaturized designs.
- Hunger Neurons Track Available Food Locations During Foraging and Spatial Memory Recall
AgRP neurons in the hypothalamus play a central role in appetitive behaviors, but their role during foraging remains unclear. In this study, we used fiber photometry to record AgRP neuron activity in freely foraging mice and found that it dynamically tracks spatial proximity to food.
- Mitochondrial–Epigenetic Pathway Linked to Age-Related Inflammation
The mitochondrial–epigenetic pathway is linked to age-related inflammation, revealing a potential therapeutic target for limiting chronic inflammation during aging.
- LLM Reads the Same Text a Thousand Times
I spent two weeks trying to make CPU inference faster. The thing that finally worked was not in the engine.
- Sanofi's New CEO Thoroughly Examines Late-Stage Pipeline Amid Clinical Clearout
New Sanofi CEO Belén Garijo opened up about her strategy to reverse a trend of clinical setbacks, including dumping Regeneron-partnered IL-33 candidate itepekimab.
- Merck Posts—Then Pulls Trial Plan for PD-1xVEGF and TROP2 ADC Combination
After nearly two years of tight-lipped secrecy, Merck & Co. briefly dropped the first concrete hint about where it intends to take its PD-1xVEGF bispecific antibody before quietly scrubbing the evidence.
- Base Editing Strategy Alleviates Huntington’s Disease in Mice
CRISPR-base editing approach reduces toxic protein fragments and disease symptoms in mouse models of Huntington's disease by precisely altering the huntingtin gene.
- Machine Learning Prediction of 6-Month Functional Outcomes in IVH Using the Brainstem Dorsal Line: A Multicenter Study
In this multicenter retrospective study, patients with Intraventricular Haemorrhage (IVH) were enrolled from nine tertiary centers in China between December 1, 2020 and December 31, 2024. The model, based on the TabICLv2 algorithm, predicts functional outcomes after IVH using a novel neuroimaging marker, the Brainstem Dorsal Line (BSDL).
- Ralinepag significantly reduces risk of clinical decline in major lung disease trial
United Therapeutics reported the full results of the phase 3 ADVANCE OUTCOMES study, showing that Ralinepag reduced the risk of a first adjudicated clinical worsening event by 55% compared to placebo.
- Intermittent Increase in CO2 Levels Promotes Glymphatic Drainage of Metabolic Waste from the Aging Brain
Researchers found that intermittent increases in carbon dioxide levels help improve glymphatic drainage, which is crucial for removing metabolic waste from aging brains.
- Launch HN: Let non-engineer staff build secure internal tools
Prized, a YC S26 startup, lets non-engineers create secure internal tools without juggling API keys or connectors. Here's a demo.
- The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Ovarian cancer cells in therapy-induced senescence secrete fructose, which enhances neighboring cancer cells' ability to detach by reducing plasma membrane cholesterol.
- Author Correction: Sleep chart of biological ageing clocks in middle and late life
This author correction presents the sleep chart of biological aging clocks in middle and late life, which was used in the original study.
- Google Reveals Gemini Robotics 2.0, Promising Improved Dexterity and Safety
New Gemini models from Google create more dexterous and safe cleaning robots. They can perform complex tasks, analyze changing environments in real-time, and work together with other robots.
- AlphaSchema: Exploring the Space of Trading Semantics for LLM-Based Alpha Mining
This paper introduces AlphaSchema, a system that constructs and explores a structured space of trading semantics for alpha mining using large language model (LLM) agents. The goal is to improve control and optimization of exploration in automated alpha mining.
- Space Force-backed Mission Does Its Best Impression of Top Gun in Orbit
Mission, backed by Space Force, best imitates 'Top Gun' in orbit. Jackal satellite (Panther) plays the role of a predator with another spacecraft Puma based on Rocket Lab's Pioneer platform.
